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Healthcare

Current Investments
AccentCare
Irvine, California
Home care services to the elderly
Archemix
Cambridge, Massachusetts
Discovery and development of aptamer-based therapeutics
AVEO Pharmaceuticals
Cambridge, Massachusetts
Discovery and development of innovative cancer therapeutics
BAROnova
Goleta, California
Novel devices for the treatment of gastrointestinal diseases
BÂRRX Medical
Sunnyvale, California
Medical device solutions for Barrett's esophagus
Fidelis SeniorCare
Schaumburg, Illinois
Comprehensive care management
Generation Health
Upper Saddle River, New Jersey
Health management company
Helicos BioSciences
Cambridge, Massachusetts
High-throughput DNA sequencing instruments
Hyperion Therapeutics
South San Francisco, California
Specialty biopharmaceuticals
iPierian
South San Francisco, California
Drug discovery and regenerative medicine
OpGen
Gaithersburg, Maryland
Microbial genome analysis
Pervasis Therapeutics
Cambridge, Massachusetts
Treatment of cardiovascular diseases
Predictive Biosciences
Lexington, Massachusetts
Novel biomarkers revolutionizing cancer management
RedBrick Health
Minneapolis, Minnesota
Consumer-directed healthcare platform
YogaWorks
Santa Monica, California
Network of alternative health fitness centers

Previous Investments
Aspect Medical Systems
Newton, Massachusetts
Anesthesia measurement devices
(Nasdaq: ASPM)
Conor Medsystems
Menlo Park, California
Second generation drug-eluting stents
(Acquired by Johnson & Johnson)
Critical Care America
Westboro, Massachusetts
Home infusion therapies
(Merged with Medical Care America, Inc.)
Delos WomensHealth
Dallas, Texas
OB/GYN physician practice management company
EXACT Sciences
Maynard, Massachusetts
Genomics-based technologies
(Nasdaq: EXAS)
GenVec
Gaithersburg, Maryland
Novel gene therapy products
(Nasdaq: GNVC)
Magen BioSciences
Waltham, Massachusetts
Dermatology and specialty pharmaceutical company
Mariner Health Group
Mystic, Connecticut
Transitional care facilities
(NYSE: MPN)
MedicaLogic/Medscape
Hillsboro, Oregon
Medical healthcare website
(Merged with MedicaLogic, Inc. to form MedicaLogic/Medscape, Inc.)
Mitotix
Cambridge, Massachusetts
Drugs to treat cancer and diseases
(Acquired by GPC Biotech)
Nations Healthcare
Atlanta, Georgia
Home care services
(Acquired by Home Medical of America)
NuGenesis Technologies
Westborough, Massachusetts
Information management solutions for the laboratory
(Acquired by Waters Corporation)
Odyssey HealthCare
Dallas, Texas
Hospice care provider
(Nasdaq: ODSY)
Ontogeny, Inc.
Cambridge, Massachusetts
Developmental biology
(Merged with Creative BioMolecules, Inc. and Reprogenesis, Inc. to form Curis, Inc.)
Origin MedSystems
Indianapolis, Indiana
Innovative surgical devices
(Acquired by Eli Lilly and Company)
PerSeptive Biosystems
Foster City, California
Biopharmaceutical products
(Acquired by The Perkin-Elmer Corporation)
PRAECIS PHARMACEUTICALS
Cambridge, Massachusetts
Drug screening processes
(Nasdaq: PRCS)
Radiant Medical
Redwood City, California
Platform technology that cools body temperature
Somatix Therapy
Atlanta, Georgia
Gene transfer technology
Theraphysics
Brentwood, Tennessee
Managed care physical therapy
(Acquired by MATRIX Rehabilitation)
Total Renal Research
Minneapolis, Minnesota
Kidney dialysis treatment centers
(Not Traded: RCGI)
UroMed
Norwood, Massachusetts
Medical products for urological disorders
(Nasdaq: URMD)
US Labs
Irvine, California
Anatomic pathology laboratory
(Acquired by LabCorp)