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Pervasis Therapeutics

Based in Cambridge, Massachusetts, Pervasis is developing cell-based therapies that induce repair and regeneration in a wide array of tissues. The company’s lead products are based on their proprietary endothelial cell technology, shown to reverse vascular dysfunction and disruption broadly. Pervasis' flagship product, Vascugel, can treat acute vascular injury in a number of clinical settings, including vascular failure and peripheral bypass failure.

By working with world leading researchers and clinicians, Pervasis has generated a rich pipeline of product opportunities and has combined advances in polymers, drug delivery and cell-based therapy. Their products bring together proprietary knowledge from the laboratories of the company's acclaimed scientific founders, Robert Langer, Elazer Edelman, Joseph Vacanti and Helen Nugent. The company’s lead program was developed with assistance from the Deshpande Center at MIT.

Recent News

Pervasis Receives Orphan Drug Designation in Europe for Vascugel to Prevent Arteriovenous Access Failure in Patients Undergoing Hemodialysis

Pervasis to Present Interim Data from Phase 1/2 Clinical Study of Novel Cell Therapy Targeting Peripheral Artery Disease at International Conference on Cell Therapy for Cardiovascular Diseases

Pervasis Therapeutics Announces $17 Million in Financing and New Board Member

Pervasis Therapeutics Announces Promising Efficacy Results from Phase 1 and 2 Clinical Trials of Vascugel® in Dialysis Patients Needing Permanent AV Access, Data Builds on Compelling Safety Findings

Pervasis Therapeutics to Present Safety and Efficacy Data from Phase 1 and 2 Clinical Trials of Vascugel® at the 35th Annual VEITHsymposium™

Pervasis Therapeutics announces New Animal Study Results Supporting Vascugel™ in Promoting Healing after Blood Vessel Injury

Pervasis Therapeutics Successfully Completes Enrollment for Vascugel™ Phase II Clinical Trials